DiHydrooxyresveratrol

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INTRODUCING

Dihydrooxyresveratrol

Skin Brightening - Anti Aging - Anti Acne
Unique and the best fairness ingredient known so far.

Dihydrooxyresveratrol

The BEST natural fairness ingredient known so far!!

Reveal your skin’s natural brilliance with nourishment for a brighter & more radiant skin. 
The most powerful skin whitening, anti-aging, wrinkle-smoothing, and anti-acne ingredient,
it’s your secret to a youthful, flawless glow.

4x brighter

 within 3 weeks

Scientifically Proven

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  • The gift of Mother nature for fairer, beautiful, flawless and glowing skin.

    Skin Whitening Properties

  • Unique and the best fairness ingredient known so far.

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  • 100% natural, Vegan

    Our products are sourced from 100% natural and vegan source. Cruelty free
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Aasha BioChem

India’s leading manufacturer of dihydrooxyresveratrol
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Dihydrooxyresveratrol is groundbreaking skincare innovation delivering unrivaled effectiveness, developed through extensive research. In today's fast-paced world, achieving and maintaining healthy, radiant skin can boost confidence and enhance overall well-being. Dihydrooxyresveratrol delivers exceptional brightening, and revitalizing benefits.

Dihydrooxyresveratrol helps to inhibit the enzyme Tyrosinase and melanin production process, effectively reducing the appearance of dark spots, melasma, and hyperpigmentation.
Human skin is continuously under threat and susceptible to damage from the environmental agents like UV Radiation, dust, smoke, humidity, climate and physiological changes. 
The demand for skin rejuvenating, anti-aging and skin brightening products is rooted in the need to eliminate localized hyper pigmentation, wrinkles and to heighten the general skin tone. With the power of Dihydrooxyresveratrol, in the formulation (Creams, Lotions and Serums) delivers a comprehensive solution for a more radiant and youthful complexion.

What is Dihydrooxyresveratrol?

Unique and the best fairness ingredient known so far.

Dihydrooxyresveratrol functions as skin brightening/whitening/lightening agent by inhibiting activity of tyrosinase enzyme. Tyrosinase is the enzyme responsible for the synthesis/ production of black pigment, melanin in human skin.
Product : Dihydrooxyresveratrol
Chemical Name : 2.4.3'.5'-Tetrahydroxy-bibenzyl
CAS No : 24082-42-6
Molecular Formula : C14H14O4
Molecular Weight : 246.25 gm/mol
Physical Properties : White Amorphous Solid.
Solubility : Soluble in water, Methanol, Ethanol, Acetone, Propylene Glycol.
Chemical Reaction : Readily reduced Fehling's solution and Tollens reagent
Recent research on skin whitening /lightening ability of natural compounds ,has identified dihydrooxyresveratrol,- with its unique abilities- as the most powerful 100% natural substance . It is identified as the best tyrosinase inhibitor known so far.

Benefits of Dihydrooxyresveratrol

The best and Unique, skin brightening/whitening, depigmenting and anti aging product from nature - better than anything known so far.

100% Natural Product

Dihydrooxyresveratrol is 100% Natural Product, isolated from The medicinal plants widely distributed in Asia

No toxicity

Dihydrooxyresveratrol showed No toxicity in human skin irritation tests

Skin Friendly

The depigmenting effect of Dihydrooxyresveratrol works through the reversible inhibition of tyrosinase activity rather than the suppression of the expression of tyrosinase enzyme.

Requires only low concentration with maximum effect

Extremely low concentration of Dihydrooxyresveratrol is enough in formulations[ 0.1 to 0.2%] -compared to all other popular products both natural and synthetic

Good water solubility and stability

Good water solubility and stability in water solution of Dihydrooxyresveratrol are extremely favorable for preparation of skin brightening/ lightening , ant aging creams, lotions, and serums compared to others.

Skin whitening, Antioxidant, & Anti-inflammatory

Recently reported skin whitening/ brightening , Antioxidant, and Anti-inflammatory activities of dihydrooxyresveratrol, position it Unique and superior to all the known antityrosinase ingredients known till date.

Natural Sources for Dihydrooxyresveratrol

Mulberry fruits and trees | Artocarpus lakoocha fruit & hard wood
Natural source for Dihydrooxyresveratrol was first identified in mulberry extracts(Morus alba). Later the compound was identified in other medicinal plants. It is also be obtained from Artocarpus lakoocha and plants belonging to the same family. Oxyresveratrol isolated from the above sources is converted to dihydrooxyresveratrol by hydrogenation reaction.

  • Mulberry fruits and tree

    Our products are sourced from 100% natural and vegan sources. 

  • Artocarpus lakoocha fruit

    Our products are sourced from 100% natural and vegan sources. 

  • Lakoocha Hard Wood

    Our products are sourced from 100% natural and vegan sources. 

Skin Whitening Potential of Dihydrooxyresveratrol

For the evaluation of tyrosinase inhibitory activity, assays were performed with L-dopa as the substrate and using kojic acid, a well-known strong tyrosinase inhibitor, as the positive control. 
It is suggested that the higher tyrosinase inhibitory activity of dihydrooxyresveratrol was probably due to its bibenzyl structure, which gave more flexibility and thus allowed the phenolic groups to interact with the enzyme more effectively.
Table 1

A comparative study of skin lightening efficacy based on the IC50 values:                                                                                                                                             

Compound

IC50

μm

Mode of activity/

Visibility



Stability  



Optimal



Source    

Tyrosinase Inhibition

Significant whitening

In formulation

Quantity In formulation

Resveratrol

54.6 μm 

Reversible

6- 8 weeks

Stable

2.0 .%

Morus Alba 

Kojic acid

40 μm 

Reversible

6-8 weeks

Stable

3 .0%

Koji ,  Shitake Reishe 

Oxyresveratrol

1.7 μm 

Reversible

2-3 weeks

Stable

0.2 -0.3 %

Artocarpus Lakoocha

Dihydrooxyresveratrol

0.3 μm 

Reversible

Less than 2/3 weeks

Stable

0.1 - 0.2 %

Morus Alba,

Artocarpus Lakoocha

 

Table 1 summarizes the IC50 values of natural products used in skin brightening/skin whitening formulations..Lower the IC50, better is the activity

Know More - Skin Whitening Properties
Table 1 summarizes the percentages of inhibition and the IC50 values of 1–4, as compared with kojic acid. Oxyresveratrol (1) was earlier reported to be stonger tyrosinase inhibitor from natural sources.

Table 1. Tyrosinase inhibition in 300 _M and 60 _M, and IC50 values of compounds isolated from Morus alba wood.

CompoundTyrosinase Inhibition
% +STD (300 _M)% +STD (60 _M)IC50 +STD (_M) *
1. Di hydro oxyresveratrol    98.2 +0.597.6 +0.20.3 +0.05
2. Oxyresveratrol 97.8 +0.193.1 +0.11.7 +0.04
3. Kojic acid96.0 +0.294.2 +0.216.1 +1.4
4. Moracin M87.2 +0.561.3 +1.28.0+ 0.6

 

Dihydrooxyresveratrol represents a pioneering advancement in skincare, emerging from rigorous research to deliver unmatched skin brightening results. In today’s dynamic environment, achieving luminous and healthy skin can greatly boost self-confidence and overall wellness. 
This innovative ingredient not only enhances radiance and revitalizes the complexion but also works by suppressing the Tyrosinase enzyme and curbing melanin production, thereby effectively diminishing dark spots, melasma, and hyperpigmentation.
By suppressing the Tyrosinase enzyme and curbing melanin production, the ingredient targets the skin’s melanin production process by modulating key enzymes involved in pigmentation. Its dual antioxidant and anti-inflammatory properties help reduce the appearance of dark spots and uneven tone, as detailed on the skin-lightening potential page, offering a scientifically supported approach to skin care.
With the lowest IC50 value, among all skin whitening ingredients, Dihyrooxyresveratrol is the best natural fairness ingredient known so far
Extensive research demonstrates that dihydrooxyresveratrol not only inhibits melanin synthesis but also promotes an overall brighter skin tone. Clinical data and comparative studies show its superior performance relative to traditional whitening agents, confirming its role as a breakthrough ingredient in modern skin care formulations.
Dihydrooxyresveratrol is available for purchase through our direct ordering system. We offer bulk orders, international shipping, and a range of custom solutions to suit your needs. For pricing details, ordering options, or any inquiries regarding our product, please contact us at 
(+91) 9497754109 or (+91) 4962524078.
Yes, dihydrooxyresveratrol is formulated with safety in mind. Extensive testing and research ensure that it is gentle enough for daily use across various skin types. As always, a patch test is recommended for those with particularly sensitive skin, but the ingredient’s robust safety profile makes it a trusted choice for enhancing skin whitening and overall skin health.

Contact Us

Aasha Biochem - India’s leading manufacturer of dihydrooxyresveratrol
Call Us : 
(+91) 9497754109
(+91) 4962524078
Email Us :
aasha_bc@yahoo.com

    DiHydrooxyresveratrol

    Aasha Biochem is India's largest, an internationally well recognized pioneer in India for the manufacture and export of Dihydrooxyresveratrol which are 100% pure and natural and are extracted from the natural resources.
    Contact Us

    (+91) 9497754109

    (+91) 4962524078

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    Vadakara - 673106,
    Kerala, India.
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